Drawing the Map of Life: Inside the Human Genome Project (A Merloyd Lawrence Book)

By Victor K. McElheny

Drawing the Map of Life is the dramatic tale of the Human Genome undertaking from its origins, in the course of the race to reserve the three billion subunits of DNA, to the surprises rising as scientists search to take advantage of the molecule of heredity. It’s the 1st account to deal intensive with the highbrow roots of the undertaking, the motivations that drove it, and the hype that regularly masked real triumphs.

Distinguished technology journalist Victor McElheny bargains vibrant, insightful profiles of key humans, reminiscent of David Botstein, Eric Lander, Francis Collins, James Watson, Michael Hunkapiller, and Craig Venter. McElheny additionally indicates that the Human Genome venture is a outstanding instance of ways new thoughts (such as restrict enzymes and sequencing tools) frequently arrive first, shaping the questions scientists then ask.

Drawing on years of unique interviews and reporting within the internal circles of organic technology, Drawing the Map of Life is the definitive, up to date tale of today’s maximum medical quest. not anyone who needs to appreciate genome mapping and the way it truly is reworking our lives can have enough money to overlook this book.

Show description

Preview of Drawing the Map of Life: Inside the Human Genome Project (A Merloyd Lawrence Book) PDF

Best Biology books

10% Human: How Your Body's Microbes Hold the Key to Health and Happiness

You're simply 10% human. for each one of many cells that make up the vessel that you just name your physique, there are 9 impostor cells hitching a journey. you're not simply flesh and blood, muscle and bone, mind and pores and skin, but additionally micro organism and fungi. Over your lifetime, you'll hold the an identical weight of 5 African elephants in microbes.

Who's in Charge?: Free Will and the Science of the Brain

“Big questions are Gazzaniga’s inventory in exchange. ”—New York Times“Gazzaniga is among the so much magnificent experimental neuroscientists on the planet. ”—Tom Wolfe“Gazzaniga stands as an immense between neuroscientists, for either the standard of his study and his skill to speak it to a basic public with infectious enthusiasm.

Fragment Based Drug Design, Volume 493: Tools, Practical Approaches, and Examples (Methods in Enzymology)

There are many very good reports on fragment-based drug discovery (FBDD), yet there are thus far no hand-holding publications or protocols with which you'll be able to embark in this orthogonal method of supplement conventional excessive throughput screening methodologies. This tools in Enzymology quantity deals the instruments, functional methods, and hit-to-lead examples on how one can behavior FBDD displays.

The Invisible History of the Human Race: How DNA and History Shape Our Identities and Our Futures

• A ny Times Notable publication •“The richest, hottest, most enjoyable e-book on genetics in your time. ” —The big apple occasions e-book evaluation we're doomed to copy background if we fail to profit from it, yet how are we suffering from the forces which are invisible to us? within the Invisible historical past of the Human Race Christine Kenneally attracts on state-of-the-art examine to bare how either historic artifacts and DNA let us know the place we come from and the place we will be going.

Additional info for Drawing the Map of Life: Inside the Human Genome Project (A Merloyd Lawrence Book)

Show sample text content

Craig Venter Institute Montana-born Leroy Hood, chief in automating Sanger’s sequencing strategy, recommend of customized drugs, founding father of prime biotech businesses, and, in 2000, the nonprofit Institute for platforms Biology, Seattle. Courtesy Institute for structures Biology, Seattle James Watson of the DNA double helix (Nobel Prize 1962), left, with Frederick Sanger, correct, first to decipher a protein (Nobel Prize 1958) and inventor of the sequencing procedure automatic for the Human Genome venture (Nobel Prize 1980). Courtesy Wellcome photos Walter Gilbert, physicist, experimental biologist, sequencer (Nobel Prize 1980), entrepreneur, enterprise capitalist, collector, and photographer. Courtesy Walter Gilbert David Botstein, yeast researcher, whose 1978 brainstorm used to be a landmark in mapping the site of genes on DNA, early skeptic concerning the Human Genome undertaking. Courtesy Lewis-Sigler Institute, Princeton collage Alec Jeffreys of Leicester collage, 1984 inventor of DNA “fingerprinting,” that is used all over the world to set up parentage, establish fragmentary is still, pinpoint criminals, and absolve the blameless. Courtesy Sir Alec Jeffreys Robert Waterston, pupil of “the worm,” C. elegans, chief of Washington University’s sequencing middle, and a common dealer between fierce rivals. Courtesy college of Washington Maynard Olson, “skeptical chemist,” occasionally consensus thinker of the Human Genome undertaking he helped plan. Courtesy collage of Washington Pieter J. de Jong, builder of “libraries” containing DNA clones, saved in rankings of freezers and utilized by researchers around the globe. Courtesy Children’s health center of Oakland learn Institute Board of administration, 2000, of the sequencing middle at Hinxton close to Cambridge, England, the place one-third of the human genome used to be sequenced. entrance (left to right): Jane Rogers, John Sulston, David Bentley, and Richard Durbin. again (left to right): Bart Barrell, Murray Cairns, Alan Coulson, and Mike Stratton. Courtesy Wellcome belief Sanger Institute Sequencing manufacturing unit at Hinxton, early 2000s, exhibiting rows of machines made through utilized Biosystems, Inc. of California; in different rooms, semiautomated coaching and “amplification” of DNA samples and desktops to crunch the information published at no cost each evening on the net.

Download PDF sample

Rated 4.85 of 5 – based on 24 votes